Pogledaj skup podataka Uredi metapodatke Promijenite redoslijed resursa Naslov * URL /ckan/bs/dataset/ Opis This dataset provides a comprehensive technical and clinical overview of Spravato (Esketamine) 56mg Nasal Spray, the first FDA-approved nasal treatment for treatment-resistant depression (TRD). Each dose kit contains two 28mg single-use devices, delivering a pharmaceutical-grade formulation that targets the brain’s NMDA receptors to promote rapid synaptogenesis. This data is essential for researchers at NIASRA and the University of Wollongong (UOW) focused on interventional psychiatry and neuroplasticity. Technical Specifications • Active Ingredient: Esketamine (the S-enantiomer of ketamine) • Concentration: 28mg per device (56mg total per Dose Kit) • Mechanism: Non-competitive NMDA receptor antagonist • Regulatory Status: FDA-Approved for TRD and suicidal ideation • Delivery Method: Intranasal (Single-use devices) Clinical & Research Applications • Rapid Antidepressant Effects: Investigating symptom relief timelines, often observed within 24 hours of administration. • Neuroplasticity & Synaptogenesis: Exploring the modulation of glutamate receptors to restore neural connections. • Treatment-Resistant Depression (TRD): Analyzing efficacy in patients who have failed to respond to at least two different oral antidepressants. • Co-Occurring Anxiety: Researching the secondary benefits of esketamine in reducing anxiety levels through neural pathway “resetting.” Patient Experience & Safety Data • Dissociative Effects: Documenting the temporary state of dissociation and sensory changes peaking at 40 minutes post-administration. • Monitoring Protocols: Analyzing the importance of post-administration observation for blood pressure and sedation. • Duration of Relief: Tracking the enduring antidepressant benefits versus the short-lived acute effects. Source Information For detailed clinical data and pharmaceutical-grade procurement, visit: https://lyfeunit.com/product/spravato-esketamine-56mg-nasal-spray-dose-kit/ You can use Markdown formatting here Oznake Licenca Odaberi licencu Creative Commons Attribution Creative Commons Attribution Share-Alike Creative Commons CCZero Creative Commons Non-Commercial (bilo koji) GNU Free Documentation License Licenca nije navedena Open Data Commons Attribution License Open Data Commons Open Database License (ODbL) Open Data Commons Public Domain Dedication and License (PDDL) Ostalo (Javna domena) Ostalo (Nekomercijalno) Ostalo (Otvoreno) Ostalo (Zatvoreno) Ostalo (s atribucijom) UK Open Government Licence (OGL) Definicije licenci i dodatne informacije možete pronaći na opendefinition.org Izvor Verzija Autor Email autora Održava E-mail održavatelja Korisnički definisano polje Ključ Vrijednost Korisnički definisano polje Ključ Vrijednost Korisnički definisano polje Ključ Vrijednost * Obavezno polje Podatkovna licenca koju ste odabrali se samo odnosi na sadržaj svih datoteka resursa koje dodate ovom skupu podataka. Slanjem ovog obrasca saglasni ste da ćete objaviti vrijednosti metapodataka koje unesete u obrazac pod licencom Open Database License . Ažuriraj skup podataka