ความเปลี่ยนแปลง

              
    

          
          
        
        

            
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  "author": "Ketalar Ketamine HCL",
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  "author": "Ketalar Ketamine HCL",
            
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  "author_email": "inquiries.lyfeunit@proton.me",
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  "author_email": "inquiries.lyfeunit@proton.me",
            
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  "creator_user_id": "5ecc116b-5ec4-48f4-8366-afe5052790b1",
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  "creator_user_id": "5ecc116b-5ec4-48f4-8366-afe5052790b1",
            
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  "license_id": "",
            
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  "license_title": "",
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  "license_title": "",
            
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  "maintainer": "",
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  "maintainer": "",
            
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  "maintainer_email": "",
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  "maintainer_email": "",
            
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  "metadata_created": "2026-06-26T16:36:51.401940",
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  "metadata_created": "2026-06-26T16:36:51.401940",
            
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  "metadata_modified": "2026-06-26T16:37:44.365410",
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  "metadata_modified": "2026-06-26T16:37:44.537219",
            
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  "name": 
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  "name": 
            
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-ketamine-hcl-injection-usp-500mg-10ml-multi-dose-vial-clinical-data",
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-ketamine-hcl-injection-usp-500mg-10ml-multi-dose-vial-clinical-data",
            
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  "notes": "This dataset provides a comprehensive technical and 
17
  "notes": "This dataset provides a comprehensive technical and 
            
18
clinical profile of Ketalar (Ketamine HCl) Injection USP, the gold 
18
clinical profile of Ketalar (Ketamine HCl) Injection USP, the gold 
            
19
standard for rapid-acting, non-barbiturate general anesthesia. Each 
19
standard for rapid-acting, non-barbiturate general anesthesia. Each 
            
20
10ml multi-dose vial contains 500mg of USP-grade Ketamine 
20
10ml multi-dose vial contains 500mg of USP-grade Ketamine 
            
21
Hydrochloride (50mg/mL), formulated to ensure profound analgesia and 
21
Hydrochloride (50mg/mL), formulated to ensure profound analgesia and 
            
22
stable hemodynamics. This data is essential for researchers at NIASRA 
22
stable hemodynamics. This data is essential for researchers at NIASRA 
            
23
and the University of Wollongong (UOW) focused on emergency medicine, 
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and the University of Wollongong (UOW) focused on emergency medicine, 
            
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pediatric anesthesia, and NMDA receptor antagonism.\r\n\r\nTechnical 
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pediatric anesthesia, and NMDA receptor antagonism.\r\n\r\nTechnical 
            
25
Specifications\r\n\t\u2022\tBrand: 
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Specifications\r\n\t\u2022\tBrand: 
            
26
Ketalar\u00ae\r\n\t\u2022\tConcentration: 50mg/mL (500mg per 10ml 
26
Ketalar\u00ae\r\n\t\u2022\tConcentration: 50mg/mL (500mg per 10ml 
            
27
Multi-Dose Vial)\r\n\t\u2022\tCAS Number: 
27
Multi-Dose Vial)\r\n\t\u2022\tCAS Number: 
            
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1867-66-9\r\n\t\u2022\tRegulatory Status: CIII Controlled Substance 
28
1867-66-9\r\n\t\u2022\tRegulatory Status: CIII Controlled Substance 
            
29
(DEA Schedule III)\r\n\t\u2022\tpH Range: 3.5 \u2013 5.5 (Sterile, 
29
(DEA Schedule III)\r\n\t\u2022\tpH Range: 3.5 \u2013 5.5 (Sterile, 
            
30
slightly acidic solution)\r\n\t\u2022\tPreservative: 0.1 mg/mL 
30
slightly acidic solution)\r\n\t\u2022\tPreservative: 0.1 mg/mL 
            
31
Benzethonium Chloride\r\n\r\nClinical & Research 
31
Benzethonium Chloride\r\n\r\nClinical & Research 
            
32
Applications\r\n\t\u2022\tGeneral Anesthesia Induction: Investigating 
32
Applications\r\n\t\u2022\tGeneral Anesthesia Induction: Investigating 
            
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rapid-onset protocols for surgical procedures and trauma-related 
33
rapid-onset protocols for surgical procedures and trauma-related 
            
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interventions.\r\n\t\u2022\tNMDA Receptor Antagonism: Exploring the 
34
interventions.\r\n\t\u2022\tNMDA Receptor Antagonism: Exploring the 
            
35
\u201cdissociative\u201d state produced by blocking excitatory 
35
\u201cdissociative\u201d state produced by blocking excitatory 
            
36
glutamate effects in the thalamocortical 
36
glutamate effects in the thalamocortical 
            
37
system.\r\n\t\u2022\tPediatric Anesthesia: Analyzing the safety 
37
system.\r\n\t\u2022\tPediatric Anesthesia: Analyzing the safety 
            
38
profile of ketamine for minor surgical procedures where respiratory 
38
profile of ketamine for minor surgical procedures where respiratory 
            
39
drive maintenance is critical.\r\n\t\u2022\tDiagnostic Sedation: 
39
drive maintenance is critical.\r\n\t\u2022\tDiagnostic Sedation: 
            
40
Studying its use as a sole agent for procedures not requiring skeletal 
40
Studying its use as a sole agent for procedures not requiring skeletal 
            
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muscle relaxation (e.g., dental extractions, eye/ear 
41
muscle relaxation (e.g., dental extractions, eye/ear 
            
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surgery).\r\n\r\nPharmacokinetics & Safety 
42
surgery).\r\n\r\nPharmacokinetics & Safety 
            
43
Data\r\n\t\u2022\tRedistribution Dynamics: Documenting the rapid 
43
Data\r\n\t\u2022\tRedistribution Dynamics: Documenting the rapid 
            
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distribution into highly vascularized tissues (brain/heart) followed 
44
distribution into highly vascularized tissues (brain/heart) followed 
            
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by muscle and adipose tissue.\r\n\t\u2022\tMetabolic Pathways: 
45
by muscle and adipose tissue.\r\n\t\u2022\tMetabolic Pathways: 
            
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Analyzing hepatic N-demethylation to the active metabolite 
46
Analyzing hepatic N-demethylation to the active metabolite 
            
47
norketamine.\r\n\t\u2022\tEmergence Phenomena: Researching the 
47
norketamine.\r\n\t\u2022\tEmergence Phenomena: Researching the 
            
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minimization of recovery-phase delirium through controlled 
48
minimization of recovery-phase delirium through controlled 
            
49
environments and co-administration strategies.\r\n\r\nSource 
49
environments and co-administration strategies.\r\n\r\nSource 
            
50
Information\r\nFor authoritative clinical data and professional-grade 
50
Information\r\nFor authoritative clinical data and professional-grade 
            
51
procurement, 
51
procurement, 
            
52
/lyfeunit.com/product/ketalar-ketamine-hcl-injection-usp-500mg-10ml/",
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      "created": "2026-06-26T16:37:44.388211",
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      "datastore_active": false,
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      "datastore_active": false,
            
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      "description": "This dataset captures the clinical heritage and 
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      "description": "This dataset captures the clinical heritage and 
            
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technical specifications of Ketalar (Ketamine HCl) Injection USP 
67
technical specifications of Ketalar (Ketamine HCl) Injection USP 
            
68
(500mg/10ml). As a cornerstone of modern anesthesia, Ketalar provides 
68
(500mg/10ml). As a cornerstone of modern anesthesia, Ketalar provides 
            
69
\u201ctechnical proof\u201d of efficacy through its unique ability to 
69
\u201ctechnical proof\u201d of efficacy through its unique ability to 
            
70
maintain cardiovascular stability and protective airway reflexes. The 
70
maintain cardiovascular stability and protective airway reflexes. The 
            
71
dataset is meticulously curated to meet the analytical standards of 
71
dataset is meticulously curated to meet the analytical standards of 
            
72
the National Institute for Applied Statistics Research Australia 
72
the National Institute for Applied Statistics Research Australia 
            
73
(NIASRA) and the University of Wollongong (UOW).\r\n\r\nClinical & 
73
(NIASRA) and the University of Wollongong (UOW).\r\n\r\nClinical & 
            
74
Technical Significance\r\nThe information detailed in this dataset is 
74
Technical Significance\r\nThe information detailed in this dataset is 
            
75
pivotal for:\r\n\r\n\t\u2022\tSympathomimetic Analysis: Understanding 
75
pivotal for:\r\n\r\n\t\u2022\tSympathomimetic Analysis: Understanding 
            
76
how Ketalar stimulates the cardiovascular system, making it ideal for 
76
how Ketalar stimulates the cardiovascular system, making it ideal for 
            
77
hemodynamically sensitive patients.\r\n\t\u2022\tPharmacokinetic 
77
hemodynamically sensitive patients.\r\n\t\u2022\tPharmacokinetic 
            
78
Modeling: Providing data on the redistribution and metabolism of the 
78
Modeling: Providing data on the redistribution and metabolism of the 
            
79
hydrochloride salt for accurate clinical 
79
hydrochloride salt for accurate clinical 
            
80
timing.\r\n\t\u2022\tProcedural Flexibility: Evaluating the benefits 
80
timing.\r\n\t\u2022\tProcedural Flexibility: Evaluating the benefits 
            
81
of a multi-dose vial optimized for both intravenous (IV) and 
81
of a multi-dose vial optimized for both intravenous (IV) and 
            
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intramuscular (IM) administration.\r\n",
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intramuscular (IM) administration.\r\n",
            
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      "name": "Ketalar (Ketamine HCl) Injection USP 500mg/10ml 
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Research Data",
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      "display_name": "Ketalar",
            
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      "id": "591e4451-6521-4c4d-87b4-1d3b8bb1f7c8",
            
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      "name": "Ketalar",
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      "name": "Ketalar",
            
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      "display_name": "NMDA Antagonist",
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      "display_name": "NMDA Antagonist",
            
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      "state": "active",
            
179
      "vocabulary_id": null
179
      "vocabulary_id": null
            
180
    },
180
    },
            
181
    {
181
    {
            
182
      "display_name": "Pharmacology",
182
      "display_name": "Pharmacology",
            
183
      "id": "7b8a5e22-8b54-44a8-97e6-0fb830dde386",
183
      "id": "7b8a5e22-8b54-44a8-97e6-0fb830dde386",
            
184
      "name": "Pharmacology",
184
      "name": "Pharmacology",
            
185
      "state": "active",
185
      "state": "active",
            
186
      "vocabulary_id": null
186
      "vocabulary_id": null
            
187
    },
187
    },
            
188
    {
188
    {
            
189
      "display_name": "UOW",
189
      "display_name": "UOW",
            
190
      "id": "db7fb5f3-4f8e-45eb-ac60-18d37318f122",
190
      "id": "db7fb5f3-4f8e-45eb-ac60-18d37318f122",
            
191
      "name": "UOW",
191
      "name": "UOW",
            
192
      "state": "active",
192
      "state": "active",
            
193
      "vocabulary_id": null
193
      "vocabulary_id": null
            
194
    },
194
    },
            
195
    {
195
    {
            
196
      "display_name": "USP Grade",
196
      "display_name": "USP Grade",
            
197
      "id": "a6ff46c0-e9d0-4a0a-a2e1-029ff59797a4",
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      "id": "a6ff46c0-e9d0-4a0a-a2e1-029ff59797a4",
            
198
      "name": "USP Grade",
198
      "name": "USP Grade",
            
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      "state": "active",
199
      "state": "active",
            
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      "vocabulary_id": null
200
      "vocabulary_id": null
            
201
    }
201
    }
            
202
  ],
202
  ],
            
203
  "title": "Ketalar (Ketamine HCl) Injection USP 500mg/10ml: Clinical 
203
  "title": "Ketalar (Ketamine HCl) Injection USP 500mg/10ml: Clinical 
            
204
Data for Anesthesia Induction & Sedation",
204
Data for Anesthesia Induction & Sedation",
            
205
  "type": "dataset",
205
  "type": "dataset",
            
206
  "url": 
206
  "url": 
            
207
/lyfeunit.com/product/ketalar-ketamine-hcl-injection-usp-500mg-10ml/",
207
/lyfeunit.com/product/ketalar-ketamine-hcl-injection-usp-500mg-10ml/",
            
208
  "version": ""
208
  "version": ""
            
209
}
209
}